MOTION AS A PHENOTYPE: THE USE OF LIVE-CELL IMAGING AND MACHINE VISUAL SCREENING TO CHARACTERIZE TRANSCRIPTION-DEPENDENT CHROMOSOME DYNAMICS

Motion as a phenotype: the use of live-cell imaging and machine visual screening to characterize transcription-dependent chromosome dynamics

Abstract Background Gene transcriptional activity is well correlated with intra-nuclear position, especially relative to the nuclear periphery, which is a region classically associated with gene silencing.Recently however, actively transcribed genes have also been found localized to the nuclear periphery in the yeast Saccharomyces cerevisiae.When g

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Establishment of microbial model communities capable of removing trace organic chemicals for biotransformation mechanisms research

Abstract Background Removal of trace organic chemicals (TOrCs) in aquatic environments has been intensively studied.Some members of natural microbial communities play a vital role in transforming chemical contaminants, however, complex microbial interactions impede us from gaining adequate understanding of TOrC biotransformation mechanisms.To simpl

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